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OKINAWA - THE LOWEST DISEASE INDEX
Although seaweed has been used in cooking and medicine for centuries, greater interest in the nutraceutical potential of seaweed was aroused after research on the influence of nutrition on the state of the cardiovascular system in Okinawa.
The "centennial concentration index" on the island is 2 times higher than in all of Japan. The islander population has the world's lowest death rate from cardiovascular and cancer diseases.
The key health and longevity factor is the use of brown and red algae with minimal heat treatment for feeding. The data served as the beginning of an in-depth study of chemical and biological properties of algae, characteristics of the influence of the compounds contained in them on the human body.
FUCUS - KING OF THE BROWN ALGAE
According to a report published in 2012 by the European Agency for the Evaluation of Medicines (EMA), Fucus vesiculosus contains polysaccharides fucoidan and laminarin, found only in brown algae, alginic acid and its salts, more than 20 different plant-based micro and macro elements, vitamins, polyphenols, pigments, lipids, amino acids, carbohydrates and fats.
Fucus from the Arctic Ocean waters among all spices of brown seaweed contains the maximum amount of fucoidan and antioxidants.
The significance of Fucus is also due to the fact that its salt composition is very close to the composition of human blood plasma and tissue fluid. Fucus contains an almost complete and well-balanced set of chemical elements that are easily absorbed, since they are in an organically bound form.
WHAT IS FUCOIDAN?
Fucoidan is a sulfated polysaccharide found in the cell walls of many species of brown seaweed. Fucus Vesiculosus is especially rich in Fucoidan, it's concentration can be up to 26% of the dry weight.
In vitro studies show that it has anti-viral and immuno-modulatory effects among the others. Fucoidan also exhibited neuro-protective, radio-protective, and anti-ulcer properties.
This polysaccharide is found only in algae and is not typical for terrestrial plants, which makes it unique!
Fucoidan was first isolated in 1913 and since then it has been actively studied at institutes in Japan, Russia and United States.
SCIENTIFIC ARTICLES & CLINICAL RESEARCH
Sulfated polysaccharides effectively inhibit SARS-CoV-2 in vitro.
The marine acid polysaccharide fucoidan has attracted attention from both the food and pharmaceutical industries due to its promising therapeutic effects.
Fucoidan is a polysaccharide that mainly consists of L-fucose and sulphate groups. Its excellent biological function is attributed to its unique biological structure.
Classical activities include antitumor, antioxidant, anticoagulant, antithrombotic, immunoregulatory, antiviral and anti-inflammatory effects.
Health benefits of fucoxanthin in the prevention of chronic disease.
Fucoxanthin is a xanthophyll carotenoid abundant in macroalgae, such as brown seaweeds.
When fucoxanthin is consumed, it can be esterified or hydrolyzed to fucoxanthinol in the gastrointestinal tract and further converted into amarouciaxanthin A in the liver.
It has a unique chemical structure that confers its biological effects.
Fucoidan extracts ameliorate acute colitis.
Inflammatory bowel diseases (IBD), such as ulcerative colitis and Crohn's disease, are an important cause of morbidity and impact significantly on quality of life. Overall, current treatments do not sustain a long-term clinical remission and are associated with adverse effects, which highlight the need for new treatment options.
Fucoidans are complex sulphated, fucose-rich polysaccharides, found in edible brown algae and are described as having multiple bioactivities including potent anti-inflammatory effects.
Review: prospects for the use of extracts and polysaccharides from marine algae to prevent and treat the diseases caused by Helicobacter pylori.
In recent years, fucoidans have been extensively studied due to the numerous interesting biological activities, including the anti-adhesive, anti-oxidative, antitoxic, immunomodulatory, anticoagulant, and anti-infection effects.
This review summarizes the data on the effects of extracts and sulfated polysaccharides of marine algae, mainly fucoidans, on pathogenic targets in Helicobacter infection.
Biological Activities of Fucoidan and the Factors mediating Therapeutic Effects: A Review of Recent Studies.
The marine acid polysaccharide fucoidan has attracted attention from both the food and pharmaceutical industries due to its promising therapeutic effects.
Fucoidan is a polysaccharide that mainly consists of L-fucose and sulphate groups. Its excellent biological function is attributed to its unique biological structure.
Supplementation of Elderly Japanese Men and Women with Fucoidan from Seaweed Increases Immune Responses to Seasonal Influenza Vaccination.
The elderly are known to have an inadequate immune response to influenza vaccine. Mekabu fucoidan (MF), a sulfated polysaccharide extracted from seaweed, was previously shown to have an immunomodulatory effect.
We therefore investigated antibody production after influenza vaccination in elderly Japanese men and women with and without oral MF intake.
